These two drugs healed Spain's first coronavirus patient
Thompson Nsisongabasi
Mar 06, 2020
A 62-year-old man who became Spain's first coronavirus patient is believed to have made a full recovery after being treated with an HIV drug, according to a report.
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Miguel Ángel Benítez was hospitalized at the Virgen del Rocio Hospital in Seville, where he received lopinavir-ritonavir, an antiretroviral drug sold under the brand name Kaletra, according to Metro UK, which cited El Pais.
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The drug - which has been used to treat HIV and AIDS for over 10 years - was combined with interferon beta, a protein that prevents cells from becoming infected and is used on people with multiple sclerosis patients, the news outlet reported.
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Santiago Moreno, head of infectious diseases at the Ram├│n y Cajal hospital in Madrid, said the "SARS-CoV-2 protease is very similar to that of HIV,ÔÇØ using another name for the novel coronavirus.
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"This enzyme is essential for the virus to replicate. The combination of lopinavir and ritonavir inhibits and blocks HIV,ÔÇØ he said, according to Metro.
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"The results that we have so far regarding its use against coronaviruses are encouraging.ÔÇØ
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Researchers in Spain cautioned that not all coronavirus patients would necessarily respond to the treatment the way Benítez did.
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But a research professor at Imperial College London said that if the widely available HIV drugs prove to be successful against COVID-19 on a large scale, they could quickly be administered to the coronavirus patients.
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"There is some evidence from laboratory studies that some HIV drugs might also be active against SARS-CoV-2 and a trial has been underway for a while using these drugs against MERS,ÔÇØ Professor Graham Cooke told Metro, referring to Middle East Respiratory Syndrome.
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— Thompson Nsisongabasi